Broccoli


Article Outline
  1. 1. Composition
  2. 2. Healing Properties
    1. 2.1. Anticancer (anticancer)
    2. 2.2. Antiinflammatory
    3. 2.3. Prostate Health
    4. 2.4. Weight Loss
    5. 2.5. Hepatic Protection
  • Disease / Symptom Treatment
    1. 0.1. Cancer Treatment / Prevention
      1. 0.1.1. Breast Cancer
      2. 0.1.2. Bladder Cancer
      3. 0.1.3. Colorectal cancer
      4. 0.1.4. Prostate Cancer
      5. 0.1.5. Liver Cancer
      6. 0.1.6. Ovarian cancer
      7. 0.1.7. Cervix carcinoma
      8. 0.1.8. Hepatocellular carcinoma (HCC)
    2. 0.2. Diabetes
    3. 0.3. Obesity
    4. 0.4. Non-Alcoholic Fatty Liver Disease (NAFLD)
  • Broccoli

    Composition

    • Broccoli sprout juice contains sulforaphanyl-amine.[1]
    • Broccoli sprouts are naturally enriched in glucoraphanin,the biological precursor to the anticancer compound sulforaphane.[1:1]
    • Vitamin C
    • Flavonoids
    • Glucosinolates

    Broccoli as good sources of calcium.

    Healing Properties

    Anticancer (anticancer)

    Antiinflammatory

    Broccoli is effective in preventing inflammatory responses.[2]

    Prostate Health

    Weight Loss

    Hepatic Protection

    (prevent damage to the liver) Dietary broccoli exerts a substantial protective effect on the liver.[3]

    • Broccoli consumption helps reduce plasma alanine aminotransferase concentrations in the liver. This is an enzyme found in the liver, normally at low levels. Increased levels of this enzyme are associated with liver damage and its level is used to screen for and/or monitor liver disease.[3:1]

    • Sulforaphane (an active compound in broccoli) protects against liver damage, indicating its potential to treat liver diseases.[2:1]

    Sulforaphane from broccoli reduces inflammation and liver cancer risk[4]

    Sulforaphane (SF), a broccoli-derived isothiocyanate, inhibits the secretion of pro-inflammatory cytokines. SF was shown to suppress liver inflammation within 24hrs of treatment. SF was not associated with any cellular toxicity, indicating the protective effect of SF against inflammatory responses. This study revealed the potential usage of broccoli-derived SF as a functional food ingredient in attenuating liver inflammation and reducing liver cancer risk development.[4:1]

    Disease / Symptom Treatment

    Cancer Treatment / Prevention

    Medicinal vegetables such as broccoli and their derivative phyto-compounds are being increasingly recognized as useful complementary treatments for cancer. Indole-3-carbinol (I3C), a natural phytochemical found in cruciferous vegetables (i.e. broccoli, cabbage or cauliflower), is considered a potential anticancer agent that prevents the development of certain types of tumors by activating tumor suppressor genes, genes involved in apoptosis and detoxification. I3C suppresses cell proliferation and induces apoptosis.[5]

    • Broccoli is effective in preventing carcinogenesis.[2:2]

    Breast Cancer

    Bladder Cancer

    Colorectal cancer

    Prostate Cancer

    Liver Cancer

    Sulforaphane from broccoli reduces inflammation and liver cancer risk[4:2]

    Sulforaphane (SF), a broccoli-derived isothiocyanate, inhibits the secretion of pro-inflammatory cytokines. SF was shown to suppress liver inflammation within 24hrs of treatment. SF was not associated with any cellular toxicity, indicating the protective effect of SF against inflammatory responses. This study revealed the potential usage of broccoli-derived SF as a functional food ingredient in attenuating liver inflammation and reducing liver cancer risk development.[4:3]

    Ovarian cancer

    Cervix carcinoma

    Hepatocellular carcinoma (HCC)

    (a form of liver cancer) Long-term consumption of whole broccoli countered development of hepatic tumorigenesis.[3:2]

    Diabetes

    Broccoli is effective in preventing diabetes.[2:3]

    Obesity

    Non-Alcoholic Fatty Liver Disease (NAFLD)

    (hepatic lipidosis) Long-term consumption of whole broccoli countered NAFLD development enhanced by a Western diet.[3:3]

    • Dietary consumption of freeze-dried broccoli was shown to lower the level of hepatic triglycerides.[3:4]
    • Dietary broccoli decreased relative liver mass.[3:5]

    1. Title: Glucoraphanin and sulforaphane evolution during juice preparation from broccoli sprouts
      Publication: Food Chemistry
      Date: 19 June 2018
      Link: Source ↩︎ ↩︎

    2. Title: Hepatic protective effects of sulforaphane through the modulation of inflammatory pathways
      Publication: Journal of Asian Natural Products Research
      Date: March 2019
      Archive: ipfs.io, cloudflare ↩︎ ↩︎ ↩︎ ↩︎

    3. Title: Dietary Broccoli Lessens Development of Fatty Liver and Liver Cancer in Mice Given Diethylnitrosamine and Fed a Western or Control Diet
      Publication: The Journal of Nutrition
      Date: Feb 2016
      Link: Source ↩︎ ↩︎ ↩︎ ↩︎ ↩︎ ↩︎

    4. Title: Sulforaphane from broccoli attenuates inflammatory hepcidin by reducing IL-6 secretion in human HepG2 cells
      Publication: Journal of Functional Foods
      Date: September 2020
      Archive: ipfs.io, cloudflare ↩︎ ↩︎ ↩︎ ↩︎

    5. Title: Phytotherapy of Prostate Cancer: How far are we?
      Publication: Clinical Oncology: Case Reports
      Date: 2018
      Link: Source ↩︎