Positive associations, of both dietary and circulating vitamin C with measures of skeletal muscle mass in middle- and older-aged men and women, suggest that dietary vitamin C intake may be useful for reducing age-related muscle loss.
Vitamin C is associated with significantly increased collagen production.
- Method of action: increased mRNA expression of procollagen and elastin in fibroblasts.[2:1]
Disease / Symptom Treatment
Sarcopenia is characterized by a progressive and generalized loss of skeletal muscle mass and strength.
Studies have shown significant positive associations between both dietary and circulating vitamin C and measures of skeletal muscle in a large cohort of free-living middle- and older-aged men and women.[1:1]
Ensuring sufficient dietary vitamin C intake, by promoting a diet rich in fruits and vegetables, may help to reduce age-related loss of skeletal muscle and thus have wide-reaching public health benefit.[1:2]
Title: Lower Dietary and Circulating Vitamin C in Middle- and Older-Aged Men and Women Are Associated with Lower Estimated Skeletal Muscle Mass
Publication: Oxford University Press: The Journal of Nutrition
Date: August 2020
Study Type: Human: Case Report
Author(s): Lucy N Lewis, Richard P G Hayhoe, Angela A Mulligan, Robert N Luben, Kay-Tee Khaw, Ailsa A Welch
Institution(s): University of East Anglia, Norwich, United Kingdom; University of Cambridge, United Kingdom
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Title: Anti-skin aging activities of green tea (Camellia sinensis in melanoma cells and human skin fibroblasts
Publication: European Journal of Integrative Medicine
Date: Dec 2020
Study Type: Human Study: In Vitro
Author(s): Puxvadee Chaikul, Tawanun Sripisut, Setinee Chanpirom, Naphatsorn Ditthawutthikul
Institution(s): Mae Fah Luang University, Thailand
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